Mstat5ab^C57BL/6By
QTL Variant Detail

Summary

• QTL variant: Mstat5ab^C57BL/6By
• Name: modifier of signal transducer and activator of transcription 5ab; C57BL/6By
• MGI ID: MGI:3588343
• QTL: Mstat5ab Location: unknown Genetic Position: Chr7, Syntenic

Variant origin

• Strain of Specimen: C57BL/6By

Variant description

• Allele Type: QTL

Notes

Mapping and Phenotype information for this QTL, its variants and associated markers

J:96602

Congenic mice were analysed to show that the activation of Stat5 can be modified by a small section of mouse Chromosome 7 between Fes (39 cM; 69.9 Mb) and Hbb (50 cM; 93.6 cM).

The congenic mouse used in this experiment is B6.C-Tyr^c H1^b Hbb^d/ByJ. This strain is commonly referred to as "HW80".

References

• Original: J:96602 Couldrey C, et al., A STAT5 modifier locus on murine chromosome 7 modulates engraftment of hematopoietic stem cells during steady-state hematopoiesis. Blood. 2005 Feb 15;105(4):1476-83
• All: 1 reference(s)