Arhgdig^tm1Caw
Targeted Allele Detail

Summary

• Symbol: Arhgdig^tm1Caw
• Name: Rho GDP dissociation inhibitor gamma; targeted mutation 1, Christopher A Walsh
• MGI ID: MGI:3588412
• Synonyms: GDIgamma^-
• Gene: Arhgdig Location: Chr17:26418157-26420324 bp, - strand Genetic Position: Chr17, 13.07 cM
• Alliance: Arhgdig^tm1Caw page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:100306
• Parent Cell Line: GS1 (ES Cell)
• Strain of Origin: 129/Sv

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: A loxp flanked neomycin resistance gene replaced the entire coding sequence. Northern blot of mutant brain samples failed to detect transcript. (J:100306)

Expression

In Mice Carrying this Mutation:

3 assay results

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Arhgdig Mutation: 8 strains or lines available

References

• Original: J:100306 Ferland RJ, et al., Characterization of Rho-GDIgamma and Rho-GDIalpha mRNA in the developing and mature brain with an analysis of mice with targeted deletions of Rho-GDIgamma. Brain Res. 2005 Aug 23;1054(1):9-21
• All: 1 reference(s)