Icam1^tm1Cws
Targeted Allele Detail

Summary

• Symbol: Icam1^tm1Cws
• Name: intercellular adhesion molecule 1; targeted mutation 1, C Wayne Smith
• MGI ID: MGI:3588437
• Synonyms: ICAM-1^-
• Gene: Icam1 Location: Chr9:20927281-20940113 bp, + strand Genetic Position: Chr9, 7.69 cM
• Alliance: Icam1^tm1Cws page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:100353
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: A puromycin resistance cassette replaced the entire coding region. Neither full-length nor alternatively spliced isoforms were detected in mutants. (J:100353)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Icam1 Mutation: 25 strains or lines available

References

• Original: J:100353 Robker RL, et al., Leukocyte migration in adipose tissue of mice null for ICAM-1 and Mac-1 adhesion receptors. Obes Res. 2004 Jun;12(6):936-40
• All: 11 reference(s)