Tg(Lck-FADD)1Hed
Transgene Detail

Summary

• Symbol: Tg(Lck-FADD)1Hed
• Name: transgene insertion 1, Stephen Hedrick
• MGI ID: MGI:3588560
• Transgene: Tg(Lck-FADD)1Hed Location: unknown
• Alliance: Tg(Lck-FADD)1Hed page

Transgene origin

• Strain of Origin: (C57BL/6 x BALB/c)F1

Transgene description

• Transgene Type: Transgenic (Inserted expressed sequence)
• Mutation: Insertion
• Tg(Lck-FADD)1Hed expresses 1 gene
  Transgene expresses:
  

  Organism

  Expressed Gene

  Homolog in Mouse

  Note

  human

  FADD (8772)

  Fadd	(MGI:109324)

• Mutation details: An AU1-tagged NFD4 truncation of human FADD coding for amino acids 80 to 208 is under the control of the proximal promoter of the murine Lck gene. The FADD insert is missing a putative death effector domain. (J:100451)

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available

References

• Original: J:100451 Walsh CM, et al., A role for FADD in T cell activation and development. Immunity. 1998 Apr;8(4):439-49
• All: 5 reference(s)