Sgk3^ypc
Spontaneous Allele Detail

Summary

• Symbol: Sgk3^ypc
• Name: serum/glucocorticoid regulated kinase 3; ypc
• MGI ID: MGI:3588656
• Synonyms: ypc
• Gene: Sgk3 Location: Chr1:9868332-9971070 bp, + strand Genetic Position: Chr1, 2.08 cM
• Alliance: Sgk3^ypc page

Mutation origin

• Strain of Origin: Not Specified

Mutation description

• Allele Type: Spontaneous
• Mutation: Single point mutation
• Mutation details: A single C-to-A transversion at coding nucleotide 1382 caused a nonsense mutation at serine codon 461 (p.S461*). Premature termination abolishes the indispensiable serine residue at the C-terminal end and results in a non-functioning protein. (J:99486)
• Inheritance: Not Specified

Expression

In Structures Affected by this Mutation:

11 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Sgk3 Mutation: 30 strains or lines available

References

• Original: J:99486 Masujin K, et al., A mutation in the serum and glucocorticoid-inducible kinase-like kinase (Sgkl) gene is associated with defective hair growth in mice. DNA Res. 2004 Dec 31;11(6):371-9
• All: 2 reference(s)