Tg(DBH-cre)6-8Koba
Transgene Detail

Summary

• Symbol: Tg(DBH-cre)6-8Koba
• Name: transgene insertion 6-8, Kazuto Kobayashi
• MGI ID: MGI:3588786
• Synonyms: DBH-cre/6-8
• Transgene: Tg(DBH-cre)6-8Koba Location: unknown
• Alliance: Tg(DBH-cre)6-8Koba page

Transgene origin

• Strain of Origin: Not Specified

Transgene description

• Transgene Type: Transgenic (Recombinase)
• Mutation: Insertion
• Tg(DBH-cre)6-8Koba expression driven by 1 gene
  Transgene expression driven by:
  

  Organism

  Driver Gene

  Homolog in Mouse

  Note

  human

  DBH (1621)

  Dbh	(MGI:94864)

• Mutation details: A cre gene with a nuclear localization signal is expressed under the control of the human dopamine beta-hydroxylase promoter. Cre activity is detected in motor neurons of the cranial nerves and spinal cord, and sensory and enteric neurons. Expression was observed in both developmental and adult stages. (J:100208, J:100207)

Recombinase activity

Activity:	Tissue activity of this recombinase allele
Driver:	DBH (human) Summary of all recombinase alleles driven by DBH. Comparative matrix view of recombinase activities Alliance human DBH gene page

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available

References

• Original: J:100207 Kobayashi K, et al., Survival of developing motor neurons mediated by Rho GTPase signaling pathway through Rho-kinase. J Neurosci. 2004 Apr 7;24(14):3480-8
• All: 7 reference(s)