Gt(ROSA)26Sor^{tm2(Wnt1/GFP)Amc}
Targeted Allele Detail

Summary

• Symbol: Gt(ROSA)26Sor^{tm2(Wnt1/GFP)Amc}
• Name: gene trap ROSA 26, Philippe Soriano; targeted mutation 2, Andrew P McMahon
• MGI ID: MGI:3589804
• Synonyms: ROSA-Wnt1
• Gene: Gt(ROSA)26Sor Location: Chr6:113044389-113054205 bp, - strand Genetic Position: Chr6, 52.73 cM
• Alliance: Gt(ROSA)26Sor^{tm2(Wnt1/GFP)Amc} page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:100575
• Parent Cell Line: AV3 (ES Cell)
• Strain of Origin: 129X1/SvJ

Mutation description

• Allele Type: Targeted (Conditional ready, Inserted expressed sequence, Reporter)
• Mutation: Insertion
• Gt(ROSA)26Sor^{tm2(Wnt1/GFP)Amc} expresses 1 gene
  Knock-in expresses:
  

  Organism	Expressed Gene	Note
  mouse	Wnt1 (MGI:98953)

• Mutation details: A full-length Wnt1-GFP construct was inserted into the locus downstream of a floxed triple polyA sequence. Upon cre expression, the cassette is removed and Wnt1-GFP is expressed. (J:100575)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Gt(ROSA)26Sor Mutation: 993 strains or lines available

References

• Original: J:100575 Carroll TJ, et al., Wnt9b plays a central role in the regulation of mesenchymal to epithelial transitions underlying organogenesis of the mammalian urogenital system. Dev Cell. 2005 Aug;9(2):283-92
• All: 8 reference(s)