Tg(Pim1-Il9)5Jcrd
Transgene Detail

Summary

• Symbol: Tg(Pim1-Il9)5Jcrd
• Name: transgene insertion 5, Jean-Christophe Renauld
• MGI ID: MGI:3590500
• Synonyms: TG5
• Transgene: Tg(Pim1-Il9)5Jcrd Location: unknown
• Alliance: Tg(Pim1-Il9)5Jcrd page

Transgene origin

• Strain of Origin: FVB/N

Transgene description

• Transgene Type: Transgenic (Inserted expressed sequence)
• Mutation: Insertion
• Tg(Pim1-Il9)5Jcrd expresses 1 gene
  Transgene expresses:
  

  Organism	Expressed Gene	Note
  mouse	Il9 (MGI:96563)

• Mutation details: A 5kb fragment of the murine Pim1 promoter drives expression of a 4.5 kb fragment of the muring Il9 gene that includes the entire coding region plus 1.5 kb of the 3' untranslated region. High levels of RNA expression were seen in all organs and high levels of biologically active protein were detected in the serum. Five founders were generated This is a representative record representing founders 5, 25, 54, 83, and 95 all of which have identical phenotypes (J:17848)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

References

• Original: J:17848 Renauld JC, et al., Thymic lymphomas in interleukin 9 transgenic mice. Oncogene. 1994 May;9(5):1327-32
• All: 15 reference(s)