Rbp7^tm1Vgl
Targeted Allele Detail

Summary

• Symbol: Rbp7^tm1Vgl
• Name: retinol binding protein 7, cellular; targeted mutation 1, Silke Vogel
• MGI ID: MGI:3590573
• Synonyms: CRBP-III^-
• Gene: Rbp7 Location: Chr4:149534144-149539435 bp, - strand Genetic Position: Chr4, 79.4 cM
• Alliance: Rbp7^tm1Vgl page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:100844
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: 129S6/SvEvTac

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: A neomycin resistance cassette replaced the region spanning from intron 1 through part of intron 3. Northern and Western blot analysis confirmed absence of transcript and protein in mutant heart tissue. (J:100844)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Rbp7 Mutation: 7 strains or lines available

References

• Original: J:100844 Piantedosi R, et al., Cellular retinol-binding protein type III is needed for retinoid incorporation into milk. J Biol Chem. 2005 Jun 24;280(25):24286-92
• All: 2 reference(s)