Sox15^tm1Yam
Targeted Allele Detail

Summary

• Symbol: Sox15^tm1Yam
• Name: SRY (sex determining region Y)-box 15; targeted mutation 1, Shinya Yamanaka
• MGI ID: MGI:3590592
• Synonyms: Sox15^-
• Gene: Sox15 Location: Chr11:69546140-69547553 bp, + strand Genetic Position: Chr11, Syntenic
• Alliance: Sox15^tm1Yam page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:100846
• Parent Cell Line: RF8 (ES Cell)
• Strain of Origin: 129S4/SvJae

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutation: Insertion
• Mutation details: An IRES-betageo was inserted into the first exon, upstream of the HMG domain. Absence of transcript was shown by Northern blot of mutant ES cells. (J:100846)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Sox15 Mutation: 14 strains or lines available

References

• Original: J:100846 Maruyama M, et al., Differential roles for Sox15 and Sox2 in transcriptional control in mouse embryonic stem cells. J Biol Chem. 2005 Jul 1;280(26):24371-9
• All: 1 reference(s)