Pvalb^tm1(cre)Arbr
Targeted Allele Detail

Summary

• Symbol: Pvalb^tm1(cre)Arbr
• Name: parvalbumin; targeted mutation 1, Silvia Arber
• MGI ID: MGI:3590684
• Synonyms: Parvalbumin-IRES-Cre, Parv-Cre, Prvlb-CRE, Pvalb^Cre, PV^cre, PV-Cre, PVCre, (PV-CRE#32)SA-09, Pv^Cre(Arbr), Pv-ires-Cre, PV^IRES-Cre
• Gene: Pvalb Location: Chr15:78075314-78090600 bp, - strand Genetic Position: Chr15, 36.93 cM, cytoband E
• Alliance: Pvalb^tm1(cre)Arbr page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:100886
• Parent Cell Line: E14 (ES Cell)
• Strain of Origin: 129P2/OlaHsd

Mutation description

• Allele Type: Targeted (Recombinase)
• Mutation: Insertion
• Pvalb^tm1(cre)Arbr expression driven by 1 gene
  Knock-in expression driven by:
  

  Organism	Driver Gene	Note
  mouse	Pvalb (MGI:97821)

• An IRES-cre-pA cassette was inserted into the 3' UTR of exon 5. (J:100886)

Recombinase activity

Activity:	Tissue activity of this recombinase allele
Driver:	Pvalb (mouse) Summary of all recombinase alleles driven by Pvalb. Comparative matrix view of recombinase activities Alliance mouse Pvalb gene page

Disease models

Expression

In Mice Carrying this Mutation:

2 assay results 6 RNA-Seq or microarray experiment(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 5 strains available Cell Lines: 0 lines available
• Carrying any Pvalb Mutation: 29 strains or lines available

References

• Original: J:100886 Hippenmeyer S, et al., A developmental switch in the response of DRG neurons to ETS transcription factor signaling. PLoS Biol. 2005 May;3(5):e159
• All: 1047 reference(s)