Tg(Ins2-cre)1Heed
Transgene Detail

Summary

• Symbol: Tg(Ins2-cre)1Heed
• Name: transgene insertion 1, Helena Edlund
• MGI ID: MGI:3603309
• Synonyms: E line, RIP1-cre, Tg(Ins1-cre)1Heed
• Transgene: Tg(Ins2-cre)1Heed Location: unknown
• Alliance: Tg(Ins2-cre)1Heed page

Transgene origin

• Strain of Origin: (C57BL/6 x CBA)F2

Transgene description

• Transgene Type: Transgenic (Recombinase)
• Mutation: Insertion
• Tg(Ins2-cre)1Heed expression driven by 1 gene
  Transgene expression driven by:
  

  Organism

  Driver Gene

  Homolog in Mouse

  Note

  rat

  Ins2 (24506)

  Ins2	(MGI:96573)

• Mutation details: A 700 bp fragment of the rat insulin 2 promoter drives expression of cre. Cre mediated recombination is seen in pancreatic beta cells. (J:48516)

Recombinase activity

Activity:	Tissue activity of this recombinase allele
Driver:	Ins2 (rat) Summary of all recombinase alleles driven by Ins2. Alliance rat Ins2 gene page

Tumor Data

List all tumor models in MMHCdb carrying Tg(Ins2-cre)1Heed

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

References

• Original: J:48516 Ahlgren U, et al., beta-cell-specific inactivation of the mouse Ipf1/Pdx1 gene results in loss of the beta-cell phenotype and maturity onset diabetes. Genes Dev. 1998 Jun 15;12(12):1763-8
• All: 10 reference(s)