Syngap1^tm1.2Mabk
Targeted Allele Detail

Summary

• Symbol: Syngap1^tm1.2Mabk
• Name: synaptic Ras GTPase activating protein 1 homolog (rat); targeted mutation 1.2, Mary B Kennedy
• MGI ID: MGI:3603311
• Synonyms: synGAP flox
• Gene: Syngap1 Location: Chr17:27160227-27191408 bp, + strand Genetic Position: Chr17, 13.6 cM
• Alliance: Syngap1^tm1.2Mabk page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:101084
• Parent Cell Line: CJ7 (ES Cell)
• Strain of Origin: 129S1/Sv-Oca2⁺ Tyr⁺ Kitl⁺

Mutation description

• Allele Type: Targeted (Conditional ready, No functional change)
• Mutation: Insertion
• Exons 4 and 9 remained flanked with loxP sites after the removal of a floxed neo cassette. (J:101084)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Syngap1 Mutation: 49 strains or lines available

References

• Original: J:101084 Knuesel I, et al., A role for synGAP in regulating neuronal apoptosis. Eur J Neurosci. 2005 Feb;21(3):611-21
• All: 3 reference(s)