Gngt1^tm1Yf
Targeted Allele Detail

Summary

• Symbol: Gngt1^tm1Yf
• Name: guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 1; targeted mutation 1, Yoshitaka Fukada
• MGI ID: MGI:3603438
• Gene: Gngt1 Location: Chr6:3993792-3997436 bp, + strand Genetic Position: Chr6, 1.81 cM, cytoband A1
• Alliance: Gngt1^tm1Yf page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:101020
• Parent Cell Line: E14 (ES Cell)
• Strain of Origin: 129P2/OlaHsd

Mutation description

• Allele Type: Targeted (Inserted expressed sequence)
• Mutation: Insertion
• Mutation details: An S74L mutation was inserted into exon 4. Immunoblots demonstrated comparable levels of proteins in mutants and wild-type animals. (J:101020)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Gngt1 Mutation: 14 strains or lines available

References

• Original: J:101020 Kassai H, et al., Farnesylation of retinal transducin underlies its translocation during light adaptation. Neuron. 2005 Aug 18;47(4):529-39
• All: 1 reference(s)