Avpr1a^tm1Sbhu
Targeted Allele Detail

Summary

• Symbol: Avpr1a^tm1Sbhu
• Name: arginine vasopressin receptor 1A; targeted mutation 1, Shuang-Bao Hu
• MGI ID: MGI:3603461
• Synonyms: Avpr1a-, Avpr1a^tm1Ifb, v1a^-, V1aRKO
• Gene: Avpr1a Location: Chr10:122284404-122289357 bp, + strand Genetic Position: Chr10, 70.36 cM, cytoband D3
• Alliance: Avpr1a^tm1Sbhu page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:105892
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: A 1.5 kb fragment of the locus starting at 31 bp downstream of the translation start site and ending at 244 bp downstream of exon 1 was replaced by a neomycin resistance cassette. (J:105892)

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Avpr1a Mutation: 35 strains or lines available

References

• Original: J:105892 Hu SB, et al., Vasopressin receptor 1a-mediated negative regulation of B cell receptor signaling. J Neuroimmunol. 2003 Feb;135(1-2):72-81
• All: 14 reference(s)