Tg(Ins2-cre)1Dh
Transgene Detail

Summary

• Symbol: Tg(Ins2-cre)1Dh
• Name: transgene insertion 1, Douglas Hanahan
• MGI ID: MGI:3603660
• Synonyms: H line, RIP7-cre
• Transgene: Tg(Ins2-cre)1Dh Location: unknown
• Alliance: Tg(Ins2-cre)1Dh page

Transgene origin

• Strain of Origin: Not Specified

Transgene description

• Transgene Type: Transgenic (Recombinase)
• Mutation: Insertion
• Tg(Ins2-cre)1Dh expression driven by 1 gene
  Transgene expression driven by:
  

  Organism

  Driver Gene

  Homolog in Mouse

  Note

  rat

  Ins2 (24506)

  Ins2	(MGI:96573)

• Mutation details: A 10 kb fragment of the rat insulin promoter drives expression of Cre. Cre mediated recombination is seen in pancreatic beta cells. (J:85042)

Recombinase activity

Activity:	Tissue activity of this recombinase allele
Driver:	Ins2 (rat) Summary of all recombinase alleles driven by Ins2. Alliance rat Ins2 gene page

Tumor Data

List all tumor models in MMHCdb carrying Tg(Ins2-cre)1Dh

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

References

• Original: J:85042 Crabtree JS, et al., Of mice and MEN1: Insulinomas in a conditional mouse knockout. Mol Cell Biol. 2003 Sep;23(17):6075-85
• All: 3 reference(s)