Slc26a6^tm1Sole
Targeted Allele Detail

Summary

• Symbol: Slc26a6^tm1Sole
• Name: solute carrier family 26, member 6; targeted mutation 1, Manoocher Soleimani
• MGI ID: MGI:3603678
• Synonyms: pat-1, Slc26a6^-
• Gene: Slc26a6 Location: Chr9:108731239-108742117 bp, + strand Genetic Position: Chr9, 59.63 cM, cytoband F2
• Alliance: Slc26a6^tm1Sole page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:101233
• Parent Cell Line: iTL1 (ES Cell)
• Strain of Origin: 129S6/SvEvTac

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: A targeting construct was designed to replace exons 1, 2, and 3 with a PGK-neo cassette. Complete absence of mRNA and protein was demonstrated in duodenum and kidneys of mutant animals. (J:101233)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Slc26a6 Mutation: 32 strains or lines available

References

• Original: J:101233 Wang Z, et al., Renal and intestinal transport defects in Slc26a6-null mice. Am J Physiol Cell Physiol. 2005 Apr;288(4):C957-65
• All: 20 reference(s)