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Sgcetm1Ygl
Targeted Allele Detail
Summary
Symbol: Sgcetm1Ygl
Name: sarcoglycan, epsilon; targeted mutation 1, Yuqing Li
MGI ID: MGI:3604206
Gene: Sgce  Location: Chr6:4674350-4747180 bp, - strand  Genetic Position: Chr6, 1.81 cM
Alliance: Sgcetm1Ygl page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:101332
Parent Cell Line:  D3 (ES Cell)
Strain of Origin:  129S2/SvPas
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutation:    Intragenic deletion
 
Mutation detailsExon 4 was deleted via cre mediated recombination. RT-PCR analysis failed to detect mRNA from mutant brain samples. Deletion of exon 4 would cause a frame shift and create a premature stop codon in exon 5 when splicing occurs between exons 3 and 5. (J:101332)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Disease models
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Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Sgce Mutation:  44 strains or lines available
Notes
This allele is maternally imprinted.
References
Original:  J:101332 Yokoi F, et al., Exclusive paternal expression and novel alternatively spliced variants of epsilon-sarcoglycan mRNA in mouse brain. FEBS Lett. 2005 Aug 29;579(21):4822-8
All:  4 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
12/10/2024
MGI 6.24
The Jackson Laboratory