Erap1^tm1Dgen
Targeted Allele Detail

Summary

• Symbol: Erap1^tm1Dgen
• Name: endoplasmic reticulum aminopeptidase 1; targeted mutation 1, Deltagen
• MGI ID: MGI:3604456
• Gene: Erap1 Location: Chr13:74787692-74841321 bp, + strand Genetic Position: Chr13, 40.48 cM, cytoband C1
• Alliance: Erap1^tm1Dgen page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:101679
• Parent Cell Line: E14 (ES Cell)
• Strain of Origin: 129P2/OlaHsd
• Project Collection: Deltagen

Mutation description

• Allele Type: Targeted (Null/knockout, Reporter)
• Mutation: Disruption caused by insertion of vector
• Mutation details: A bacterial lacZ gene was inserted into the gene such that the endogenous gene promoter drives expression of beta-galactosidase. While RT-PCR analysis detects a gene transcript in all tissues analyzed, beta-galactosidase expression from this allele is detectable in brain, spleen, liver, kidney, trachea, larynx, thyroid gland, pituitary gland, adrenal glands, skin, male and female reproductive systems.

Expression

In Mice Carrying this Mutation:	72 assay results
In Structures Affected by this Mutation:	2 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Erap1 Mutation: 59 strains or lines available

Notes

See also, data as provided by Deltagen, Inc.

References

• Original: J:101679 Deltagen Inc, NIH initiative supporting placement of Deltagen, Inc. mice into public repositories. MGI Direct Data Submission. 2005
• All: 1 reference(s)