Grm7^tm1Dgen
Targeted Allele Detail

Summary

• Symbol: Grm7^tm1Dgen
• Name: glutamate receptor, metabotropic 7; targeted mutation 1, Deltagen
• MGI ID: MGI:3604484
• Gene: Grm7 Location: Chr6:110622542-111544191 bp, + strand Genetic Position: Chr6, 51.19 cM
• Alliance: Grm7^tm1Dgen page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:101679
• Parent Cell Line: E14 (ES Cell)
• Strain of Origin: 129P2/OlaHsd
• Project Collection: Deltagen

Mutation description

• Allele Type: Targeted (Null/knockout, Reporter)
• Mutation: Disruption caused by insertion of vector
• Mutation details: A bacterial lacZ gene was inserted into the gene such that the endogenous gene promoter drives expression of beta-galactosidase. RT-PCR analysis detects a gene transcript in brain, spinal cord, eye, heart, kidney, pituitary gland, adrenal gland, stomach, large intestine, seminal vesicle, coagulating gland, ovary and uterus; beta-galactosidase expression is detectable in brain, spinal cord, eye, spleen, lymph nodes, esophagus, parathyroid gland, pituitary gland, salivary glands, tongue, male and female reproductive systems.

Expression

In Mice Carrying this Mutation:

86 assay results

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Grm7 Mutation: 125 strains or lines available

Notes

See also, data as provided by Deltagen, Inc.

References

• Original: J:101679 Deltagen Inc, NIH initiative supporting placement of Deltagen, Inc. mice into public repositories. MGI Direct Data Submission. 2005
• All: 6 reference(s)