Gria3^tm1Dgen
Targeted Allele Detail

Summary

• Symbol: Gria3^tm1Dgen
• Name: glutamate receptor, ionotropic, AMPA3 (alpha 3); targeted mutation 1, Deltagen
• MGI ID: MGI:3604486
• Gene: Gria3 Location: ChrX:40489731-40767478 bp, + strand Genetic Position: ChrX, 23.19 cM
• Alliance: Gria3^tm1Dgen page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:101679
• Parent Cell Line: E14 (ES Cell)
• Strain of Origin: 129P2/OlaHsd
• Project Collection: Deltagen

Mutation description

• Allele Type: Targeted (Null/knockout, Reporter)
• Mutation: Insertion
• Mutation details: A bacterial lacZ gene was inserted into the gene such that the endogenous gene promoter drives expression of beta-galactosidase. RT-PCR analysis detects a gene transcript in the brain, cortex, subcortical region, cerebellum, brainstem, olfactory bulb, adrenal gland and salivary gland; beta-galactosidase expression is detectable in most tissues.

Expression

In Mice Carrying this Mutation:	62 assay results
In Structures Affected by this Mutation:	1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 2 strains available Cell Lines: 0 lines available
• Carrying any Gria3 Mutation: 12 strains or lines available

Notes

See also, data as provided by Deltagen, Inc.

References

• Original: J:101679 Deltagen Inc, NIH initiative supporting placement of Deltagen, Inc. mice into public repositories. MGI Direct Data Submission. 2005
• All: 8 reference(s)