Gabbr1^tm1Dgen
Targeted Allele Detail

Summary

• Symbol: Gabbr1^tm1Dgen
• Name: gamma-aminobutyric acid type B receptor subunit 1; targeted mutation 1, Deltagen
• MGI ID: MGI:3604487
• Gene: Gabbr1 Location: Chr17:37356888-37385197 bp, + strand Genetic Position: Chr17, 19.16 cM
• Alliance: Gabbr1^tm1Dgen page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:101679
• Parent Cell Line: E14 (ES Cell)
• Strain of Origin: 129P2/OlaHsd
• Project Collection: Deltagen

Mutation description

• Allele Type: Targeted (Hypomorph, Reporter)
• Mutation: Insertion
• Mutation details: A bacterial lacZ gene was inserted into the gene such that the endogenous gene promoter drives expression of beta-galactosidase. RT-PCR analysis detects a gene transcript in most tissues except the Harderian gland, liver and pancreas, beta-galactosidase expression is detectable in most tissues including the Harderian gland.

Expression

In Mice Carrying this Mutation:	134 assay results
In Structures Affected by this Mutation:	2 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Gabbr1 Mutation: 73 strains or lines available

Notes

See also, data as provided by Deltagen, Inc.

References

• Original: J:101679 Deltagen Inc, NIH initiative supporting placement of Deltagen, Inc. mice into public repositories. MGI Direct Data Submission. 2005
• All: 1 reference(s)