Nucb2^{Gt(OST287865)Lex}
Gene trapped Allele Detail

Summary

• Symbol: Nucb2^{Gt(OST287865)Lex}
• Name: nucleobindin 2; gene trap OST287865, Lexicon Genetics
• MGI ID: MGI:3604493
• Synonyms: Nucb2^{Gt(neo)697Lex}
• Gene: Nucb2 Location: Chr7:116103604-116139819 bp, + strand Genetic Position: Chr7, 61.79 cM
• Alliance: Nucb2^{Gt(OST287865)Lex} page

Mutation origin

• Mutant Cell Line: OST287865
• Germline Transmission: Earliest citation of germline transmission: J:103485
• Parent Cell Line: Lex-1 (ES Cell)
• Strain of Origin: 129S5/SvEvBrd
• Project Collection: Lexicon

Mutation description

• Allele Type: Gene trapped (Null/knockout, Reporter)
• Mutation: Insertion of gene trap vector
• Mutation details: Retroviral insertion occurred within the intron between the first and second non-coding exons. RT-PCR analysis revealed that transcript was absent in homozygous mice. (J:103485)
• Sequence Tags: Sequence tag details (1 tag)

  Tag ID	GenBank ID	Method	Tag Location (trapped strand)*	Select
  OST287865	CG608096 ; (MGI Seq Detail)	3' RACE	Chr7:116108690-116108835 bp (+)
  * GRCm39; (strand of gene trap mutagenesis)

• Genome Context: Genome Browser view of this mutation;

  2 gene trap insertions have trapped this gene; View all gene trap sequence tags in this region

Expression

In Structures Affected by this Mutation:

2 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 2 strains available Cell Lines: 1 line available
• Carrying any Nucb2 Mutation: 30 strains or lines available

Notes

See also, data as provided by Lexicon Genetics, Inc.

References

• Original: J:103485 Lexicon Genetics Inc, NIH initiative supporting placement of Lexicon Genetics, Inc. mice into public repositories. MGI Direct Data Submission. 2005
• All: 2 reference(s)