Fzd6^tm1Dgen
Targeted Allele Detail

Summary

• Symbol: Fzd6^tm1Dgen
• Name: frizzled class receptor 6; targeted mutation 1, Deltagen
• MGI ID: MGI:3604497
• Gene: Fzd6 Location: Chr15:38869673-38901587 bp, + strand
• Alliance: Fzd6^tm1Dgen page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:101679
• Parent Cell Line: E14 (ES Cell)
• Strain of Origin: 129P2/OlaHsd
• Project Collection: Deltagen

Mutation description

• Allele Type: Targeted (Null/knockout, Reporter)
• Mutation: Disruption caused by insertion of vector
• Mutation details: A bacterial lacZ gene was inserted into the gene such that the endogenous gene promoter drives expression of beta-galactosidase. RT-PCR analysis detects a low level of gene transcript in all tissues tested. Beta-galactosidase expression from this allele is detectable in brain, heart, pituitary gland, tongue, skin, male and female reproductive system. The most striking expression is seen in endothelial cells of blood vessels.

Expression

In Mice Carrying this Mutation:

87 assay results

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Fzd6 Mutation: 42 strains or lines available

Notes

See also, data as provided by Deltagen, Inc.

References

• Original: J:101679 Deltagen Inc, NIH initiative supporting placement of Deltagen, Inc. mice into public repositories. MGI Direct Data Submission. 2005
• All: 1 reference(s)