Adcy7^tm1Dgen
Targeted Allele Detail

Summary

• Symbol: Adcy7^tm1Dgen
• Name: adenylate cyclase 7; targeted mutation 1, Deltagen
• MGI ID: MGI:3604498
• Gene: Adcy7 Location: Chr8:88999031-89056590 bp, + strand Genetic Position: Chr8, 43.06 cM
• Alliance: Adcy7^tm1Dgen page

Mutation origin

• Mutant Cell Line: 4302
• Germline Transmission: Earliest citation of germline transmission: J:101679
• Parent Cell Line: E14 (ES Cell)
• Strain of Origin: 129P2/OlaHsd
• Project Collection: Deltagen

Mutation description

• Allele Type: Targeted (Null/knockout, Reporter)
• Mutation: Insertion
• Mutation details: A bacterial lacZ gene was inserted into the gene such that the endogenous gene promoter drives expression of beta-galactosidase. The highest levels of RNA transcripts are detectable in lymph nodes and adrenal gland. Moderate levels of RNA transcripts are detectable in lung, spleen, thymus, skin, gallbladder, urinary bladder, pituitary gland, testis, epididymis, prostate gland, ovary, uterus and white fat. LacZ expression was detected in: brain, thymus, spleen, lymph nodes, bone marrow, aorta, heart, lung, pancreas, kidney, urinary bladder, thyroid gland, skeletal muscle, skin, testis, prostate gland, ovary and uterus.

Expression

In Mice Carrying this Mutation:

30 assay results

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Adcy7 Mutation: 60 strains or lines available

Notes

See also, data as provided by Deltagen, Inc.

References

• Original: J:101679 Deltagen Inc, NIH initiative supporting placement of Deltagen, Inc. mice into public repositories. MGI Direct Data Submission. 2005
• All: 2 reference(s)