Chst3^tm1Dgen
Targeted Allele Detail

Summary

• Symbol: Chst3^tm1Dgen
• Name: carbohydrate sulfotransferase 3; targeted mutation 1, Deltagen
• MGI ID: MGI:3604509
• Synonyms: C6ST-1 KO
• Gene: Chst3 Location: Chr10:60017354-60055082 bp, - strand Genetic Position: Chr10, 29.7 cM, cytoband C
• Alliance: Chst3^tm1Dgen page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:101679
• Parent Cell Line: E14 (ES Cell)
• Strain of Origin: 129P2/OlaHsd
• Project Collection: Deltagen

Mutation description

• Allele Type: Targeted (Null/knockout, Reporter)
• Mutation: Insertion
• Mutation details: A bacterial lacZ gene was inserted into the gene such that the endogenous gene promoter drives expression of beta-galactosidase. RNA transcripts are normally detectable in spleen and lymph nodes, spinal cord, eye, lung, pancreas, adrenal gland, stomach, testis, ovary, whole brain, cortex, subcortical region, cerebellum, brainstem, olfactory bulb, Harderian glands, heart, liver, kidney, thymus, bone marrow, skin, gallbladder, urinary bladder, pituitary gland, salivary gland, skeletal muscle, tongue, small intestine, cecum, colon, epididymis, seminal vesicle, coagulating gland, prostate gland, uterus and white fat. Strong lacZ expression was detected in most organs examined. LacZ expression was not detected in gallbladder and uterus.

Disease models

Expression

In Mice Carrying this Mutation:

96 assay results

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Chst3 Mutation: 17 strains or lines available

Notes

See also, data as provided by Deltagen, Inc.

References

• Original: J:101679 Deltagen Inc, NIH initiative supporting placement of Deltagen, Inc. mice into public repositories. MGI Direct Data Submission. 2005
• All: 2 reference(s)