Adipor1^tm1Dgen
Targeted Allele Detail

Summary

• Symbol: Adipor1^tm1Dgen
• Name: adiponectin receptor 1; targeted mutation 1, Deltagen
• MGI ID: MGI:3604517
• Gene: Adipor1 Location: Chr1:134343116-134361089 bp, + strand Genetic Position: Chr1, 58.22 cM, cytoband E4
• Alliance: Adipor1^tm1Dgen page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:122027
• Parent Cell Line: E14 (ES Cell)
• Strain of Origin: 129P2/OlaHsd
• Project Collection: Deltagen

Mutation description

• Allele Type: Targeted (Null/knockout, Reporter)
• Mutation: Insertion
• Mutation details: A bacterial lacZ gene was inserted into the gene such that the endogenous gene promoter drives expression of beta-galactosidase. RNA transcripts are detectable in liver, gallbladder, urinary bladder, pituitary gland, adrenal gland, testis, coagulating gland, prostate gland, ovary, whole brain, cortex, subcortical region, cerebellum, brainstem, olfactory bulb, spinal cord, eye, Harderian glands, heart, lung, pancreas, kidney, spleen, thymus, lymph nodes, bone marrow, skin, salivary gland, skeletal muscle, tongue, stomach, small intestine, cecum, colon, epididymis, seminal vesicle, uterus and white fat. LacZ expression was detected in testis with moderate staining observed in some spermatogenic cells of the seminiferous tubules. (J:122027)

Expression

In Mice Carrying this Mutation:	52 assay results 1 RNA-Seq or microarray experiment(s)
In Structures Affected by this Mutation:	4 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Adipor1 Mutation: 45 strains or lines available

Notes

See also, data as provided by Deltagen, Inc.

References

• Original: J:122027 Bjursell M, et al., Opposing effects of adiponectin receptors 1 and 2 on energy metabolism. Diabetes. 2007 Mar;56(3):583-93
• All: 20 reference(s)