Htr1f^tm1Dgen
Targeted Allele Detail

Summary

• Symbol: Htr1f^tm1Dgen
• Name: 5-hydroxytryptamine (serotonin) receptor 1F; targeted mutation 1, Deltagen
• MGI ID: MGI:3604523
• Gene: Htr1f Location: Chr16:64745092-64926147 bp, - strand Genetic Position: Chr16, 37.1 cM
• Alliance: Htr1f^tm1Dgen page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:101679
• Parent Cell Line: E14 (ES Cell)
• Strain of Origin: 129P2/OlaHsd
• Project Collection: Deltagen

Mutation description

• Allele Type: Targeted (Null/knockout, Reporter)
• Mutation: Insertion
• Mutation details: A bacterial lacZ gene was inserted into the gene such that the endogenous gene promoter drives expression of beta-galactosidase. Low levels of RNA transcripts are detectable in brain, cortex, subcortical region, brainstem, olfactory bulb, large intestine, cecum and testis. No RNA transcripts are detectable in cerebellum, spinal cord, eye, Harderian glands, heart, lung, liver, pancreas, kidney, spleen, thymus, lymph nodes, bone marrow, skin, gallbladder, urinary bladder, pituitary gland, adrenal gland, salivary gland, skeletal muscle, tongue, stomach, small intestine, epididymis, seminal vesicle, coagulating gland, prostate gland, ovaries, uterus and white fat. LacZ (beta-galactosidase) expression is detectable in brain, spinal cord, pituitary gland and testis. Most striking expression is observed in brain.

Expression

In Mice Carrying this Mutation:

61 assay results

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Htr1f Mutation: 28 strains or lines available

Notes

See also, data as provided by Deltagen, Inc.

References

• Original: J:101679 Deltagen Inc, NIH initiative supporting placement of Deltagen, Inc. mice into public repositories. MGI Direct Data Submission. 2005
• All: 1 reference(s)