Capn5^tm1Dgen
Targeted Allele Detail

Summary

• Symbol: Capn5^tm1Dgen
• Name: calpain 5; targeted mutation 1, Deltagen
• MGI ID: MGI:3604529
• Gene: Capn5 Location: Chr7:97770766-97827481 bp, - strand Genetic Position: Chr7, 53.57 cM
• Alliance: Capn5^tm1Dgen page

Mutation origin

• Mutant Cell Line: 1385
• Germline Transmission: Earliest citation of germline transmission: J:101679
• Parent Cell Line: E14 (ES Cell)
• Strain of Origin: 129P2/OlaHsd
• Project Collection: Deltagen

Mutation description

• Allele Type: Targeted (Null/knockout, Reporter)
• Mutation: Disruption caused by insertion of vector
• Mutation details: A bacterial lacZ gene was inserted into the gene such that the endogenous gene promoter drives expression of beta-galactosidase. RNA transcripts are detectable in salivary gland, subcortical region of the brain, cerebellum, brainstem, olfactory bulb, spinal cord, eye, Harderian glands, lung, liver, pancreas, kidney, spleen, thymus, bone marrow, skin, gallbladder, urinary bladder, stomach, large intestine, cecum, epididymis, seminal vesicle, coagulating gland, prostate gland, ovaries and uterus. Striking lacZ (beta-galactosidase) expression is detectable in brain, spinal cord and ganglia. Other tissues displaying X-Gal staining are kidney, urinary bladder, salivary glands, and male reproductive system.

Expression

In Mice Carrying this Mutation:

112 assay results

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Capn5 Mutation: 48 strains or lines available

Notes

See also, data as provided by Deltagen, Inc.

References

• Original: J:101679 Deltagen Inc, NIH initiative supporting placement of Deltagen, Inc. mice into public repositories. MGI Direct Data Submission. 2005
• All: 2 reference(s)