Ctsc^tm1Dgen
Targeted Allele Detail

Summary

• Symbol: Ctsc^tm1Dgen
• Name: cathepsin C; targeted mutation 1, Deltagen
• MGI ID: MGI:3604533
• Gene: Ctsc Location: Chr7:87927293-87960096 bp, + strand Genetic Position: Chr7, 49.11 cM, cytoband D3-E1.1
• Alliance: Ctsc^tm1Dgen page

Mutation origin

• Mutant Cell Line: 1702
• Germline Transmission: Earliest citation of germline transmission: J:101679
• Parent Cell Line: E14 (ES Cell)
• Strain of Origin: 129P2/OlaHsd
• Project Collection: Deltagen

Mutation description

• Allele Type: Targeted (Null/knockout, Reporter)
• Mutation: Disruption caused by insertion of vector
• Mutation details: A bacterial lacZ gene was inserted into the gene such that the endogenous gene promoter drives expression of beta-galactosidase. RNA transcripts are normally detectable in all tissues analyzed. LacZ (beta-galactosidase) expression is detectable in brain, spinal cord, lung, pancreas, esophagus, salivary glands, tongue, skin and male reproductive systems.

Disease models

Expression

In Mice Carrying this Mutation:

67 assay results

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Ctsc Mutation: 37 strains or lines available

Notes

See also, data as provided by Deltagen, Inc.

References

• Original: J:101679 Deltagen Inc, NIH initiative supporting placement of Deltagen, Inc. mice into public repositories. MGI Direct Data Submission. 2005
• All: 2 reference(s)