Ccr1l1^tm1Dgen
Targeted Allele Detail

Summary

• Symbol: Ccr1l1^tm1Dgen
• Name: C-C motif chemokine receptor 1 like 1; targeted mutation 1, Deltagen
• MGI ID: MGI:3604539
• Gene: Ccr1l1 Location: Chr9:123777280-123778445 bp, - strand Genetic Position: Chr9, 75.05 cM, cytoband F
• Alliance: Ccr1l1^tm1Dgen page

Mutation origin

• Mutant Cell Line: 7518
• Germline Transmission: Earliest citation of germline transmission: J:101679
• Parent Cell Line: E14 (ES Cell)
• Strain of Origin: 129P2/OlaHsd
• Project Collection: Deltagen

Mutation description

• Allele Type: Targeted (Null/knockout, Reporter)
• Mutation: Disruption caused by insertion of vector
• Mutation details: A bacterial lacZ gene was inserted into the gene such that the endogenous gene promoter drives expression of beta-galactosidase. While RT-PCR analysis detects a high level of gene transcript in lymph nodes, bone marrow, pituitary gland, small intestine, prostate gland, ovary and uterus, beta-galactosidase expression from this allele is not detectable.

Phenotypes

Key:

hm	homozygous	ht	heterozygous	tg	involves transgenes	√	phenotype observed
cn	conditional genotype	cx	complex: > 1 genome feature	ot	other: hemizygous, indeterminate,...	N	normal phenotype

Genotype/
Background:

	Allelic Composition	Genetic Background	Cell Line(s)
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hm1	Ccr1l1^tm1Dgen/Ccr1l1^tm1Dgen	involves: 129P2/OlaHsd * C57BL/6

Phenotypes:

Affected Systems	hm1
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normal phenotype	√
no abnormal phenotype detected	√

View phenotypes and curated references for all genotypes (concatenated display).

Expression

In Mice Carrying this Mutation:

36 assay results

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 2 strains available Cell Lines: 0 lines available
• Carrying any Ccr1l1 Mutation: 11 strains or lines available

Notes

See also, data as provided by Deltagen, Inc.

References

• Original: J:101679 Deltagen Inc, NIH initiative supporting placement of Deltagen, Inc. mice into public repositories. MGI Direct Data Submission. 2005
• All: 1 reference(s)