Ccr6^tm1Dgen
Targeted Allele Detail

Summary

• Symbol: Ccr6^tm1Dgen
• Name: C-C motif chemokine receptor 6; targeted mutation 1, Deltagen
• MGI ID: MGI:3604541
• Gene: Ccr6 Location: Chr17:8454875-8475973 bp, + strand Genetic Position: Chr17, 4.9 cM, cytoband A1
• Alliance: Ccr6^tm1Dgen page

Mutation origin

• Mutant Cell Line: 3589
• Germline Transmission: Earliest citation of germline transmission: J:101679
• Parent Cell Line: E14 (ES Cell)
• Strain of Origin: 129P2/OlaHsd
• Project Collection: Deltagen

Mutation description

• Allele Type: Targeted (Null/knockout, Reporter)
• Mutation: Insertion
• Mutation details: A bacterial lacZ gene was inserted into the gene such that the endogenous gene promoter drives expression of beta-galactosidase. While RT-PCR analysis detects a high level of gene transcript in spleen and lymph nodes, and a lower level in lung, pancreas, thymus, bone marrow, skeletal muscle, stomach, small intestine, large intestine, cecum, testis, epididymis, seminal vesicle, coagulating gland and prostate gland, beta-galactosidase expression from this allele is detectable only in spleen and lymph nodes.

Expression

In Mice Carrying this Mutation:

56 assay results

Tumor Data

List all tumor models in MMHCdb carrying Ccr6^tm1Dgen

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 2 strains available Cell Lines: 0 lines available
• Carrying any Ccr6 Mutation: 37 strains or lines available

Notes

See also, data as provided by Deltagen, Inc.

References

• Original: J:101679 Deltagen Inc, NIH initiative supporting placement of Deltagen, Inc. mice into public repositories. MGI Direct Data Submission. 2005
• All: 45 reference(s)