Sstr1^tm1Dgen
Targeted Allele Detail

Summary

• Symbol: Sstr1^tm1Dgen
• Name: somatostatin receptor 1; targeted mutation 1, Deltagen
• MGI ID: MGI:3604559
• Gene: Sstr1 Location: Chr12:58258558-58260673 bp, + strand Genetic Position: Chr12, 25.61 cM
• Alliance: Sstr1^tm1Dgen page

Mutation origin

• Mutant Cell Line: 4113
• Germline Transmission: Earliest citation of germline transmission: J:101679
• Parent Cell Line: E14 (ES Cell)
• Strain of Origin: 129P2/OlaHsd
• Project Collection: Deltagen

Mutation description

• Allele Type: Targeted (Null/knockout, Reporter)
• Mutation: Insertion
• Mutation details: A bacterial lacZ gene was inserted into the gene such that the endogenous gene promoter drives expression of beta-galactosidase. While RT-PCR analysis detects high levels of gene transcript in pituitary gland and large intestine and lower levels in brain, cortex, subcortical region, cerebellum, brainstem, olfactory bulb, spinal cord, eye, Harderian gland, lung, spleen, lymph nodes, skin, gallbladder, urinary bladder, adrenal gland, stomach, small intestine, cecum, epididymis, prostate gland, ovaries, uterus and white fat, beta-galactosidase expression from this allele is detectable in brain, trachea, larynx, pituitary gland, tongue, and the male reproductive system.

Expression

In Mice Carrying this Mutation:	67 assay results
In Structures Affected by this Mutation:	1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Sstr1 Mutation: 22 strains or lines available

Notes

See also, data as provided by Deltagen, Inc.

References

• Original: J:101679 Deltagen Inc, NIH initiative supporting placement of Deltagen, Inc. mice into public repositories. MGI Direct Data Submission. 2005
• All: 1 reference(s)