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Slc40a1tm1Dgen
Targeted Allele Detail
Summary
Symbol: Slc40a1tm1Dgen
Name: solute carrier family 40 (iron-regulated transporter), member 1; targeted mutation 1, Deltagen
MGI ID: MGI:3604568
Gene: Slc40a1  Location: Chr1:45947228-45965683 bp, - strand  Genetic Position: Chr1, 23.96 cM, cytoband B
Alliance: Slc40a1tm1Dgen page
Mutation
origin
Mutant Cell Line:  5501
Germline Transmission:  Earliest citation of germline transmission: J:101679
Parent Cell Line:  E14 (ES Cell)
Strain of Origin:  129P2/OlaHsd
Project Collection: Deltagen
Mutation
description
Allele Type:    Targeted (Null/knockout, Reporter)
Mutation:    Insertion
 
Mutation detailsA bacterial lacZ gene was inserted into the gene such that the endogenous gene promoter drives expression of beta-galactosidase. While RNA transcripts are detectable in liver, kidney, spleen, thymus, bone marrow, skin, gallbladder, adrenal gland, salivary gland, stomach, small intestine, colon, ovary, and uterus, beta-galactosidase expression from this allele is detectable in brain, spinal cord, eyes, thymus, spleen, bone marrow, heart, lung, liver, pancreas, kidney, urinary bladder, thyroid gland, trachea, pituitary gland, adrenal glands, skeletal muscle, skin, ovary, uterus and cervix.
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Mice Carrying this Mutation: 114 assay results
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Slc40a1 Mutation:  54 strains or lines available
Notes
See also, data as provided by Deltagen, Inc.
References
Original:  J:101679 Deltagen Inc, NIH initiative supporting placement of Deltagen, Inc. mice into public repositories. MGI Direct Data Submission. 2005;
All:  2 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
11/05/2024
MGI 6.24
The Jackson Laboratory