Mmp17^tm1Dgen
Targeted Allele Detail

Summary

• Symbol: Mmp17^tm1Dgen
• Name: matrix metallopeptidase 17; targeted mutation 1, Deltagen
• MGI ID: MGI:3604575
• Gene: Mmp17 Location: Chr5:129661233-129688163 bp, + strand Genetic Position: Chr5, 68.18 cM
• Alliance: Mmp17^tm1Dgen page

Mutation origin

• Mutant Cell Line: 3177
• Germline Transmission: Earliest citation of germline transmission: J:101679
• Parent Cell Line: E14 (ES Cell)
• Strain of Origin: 129P2/OlaHsd
• Project Collection: Deltagen

Mutation description

• Allele Type: Targeted (Null/knockout, Reporter)
• Mutation: Disruption caused by insertion of vector
• Mutation details: A bacterial lacZ gene was inserted into the gene such that the endogenous gene promoter drives expression of beta-galactosidase. RT-PCR analysis detects a gene transcript in most tissues except liver and bone marrow; beta-galactosidase expression is detectable in all tissues examined primarily in the smooth muscle cells of blood vessels.

Expression

In Mice Carrying this Mutation:

145 assay results

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Mmp17 Mutation: 34 strains or lines available

Notes

See also, data as provided by Deltagen, Inc.

References

• Original: J:101679 Deltagen Inc, NIH initiative supporting placement of Deltagen, Inc. mice into public repositories. MGI Direct Data Submission. 2005
• All: 1 reference(s)