Ntsr1^tm1Dgen
Targeted Allele Detail

Summary

• Symbol: Ntsr1^tm1Dgen
• Name: neurotensin receptor 1; targeted mutation 1, Deltagen
• MGI ID: MGI:3604581
• Synonyms: Ntsr1^-
• Gene: Ntsr1 Location: Chr2:180141769-180186772 bp, + strand Genetic Position: Chr2, 103.04 cM, cytoband H1-H4
• Alliance: Ntsr1^tm1Dgen page

Mutation origin

• Mutant Cell Line: 6706
• Germline Transmission: Earliest citation of germline transmission: J:101679
• Parent Cell Line: E14 (ES Cell)
• Strain of Origin: 129P2/OlaHsd
• Project Collection: Deltagen

Mutation description

• Allele Type: Targeted (Null/knockout, Reporter)
• Mutation: Insertion
• Mutation details: A bacterial lacZ gene was inserted into the gene such that the endogenous gene promoter drives expression of beta-galactosidase. RT-PCR analysis detects a gene transcript at high levels in whole brain, subcortical region and epididymis and lower levels in cortex, brainstem, olfactory bulb, spinal cord, eye, thymus, pituitary gland, cerebellum, gallbladder, small intestine, large intestine, cecum, testis and prostate gland; weak beta-galactosidase expression is detectable in a few regions of the wholemount brain and in a small number of spermatogenic cells in the testis.

Expression

In Mice Carrying this Mutation:

29 assay results

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Ntsr1 Mutation: 31 strains or lines available

Notes

See also, data as provided by Deltagen, Inc.

References

• Original: J:101679 Deltagen Inc, NIH initiative supporting placement of Deltagen, Inc. mice into public repositories. MGI Direct Data Submission. 2005
• All: 6 reference(s)