Gabra3^tm1Dgen
Targeted Allele Detail

Summary

• Symbol: Gabra3^tm1Dgen
• Name: gamma-aminobutyric acid type A receptor subunit alpha 3; targeted mutation 1, Deltagen
• MGI ID: MGI:3604586
• Gene: Gabra3 Location: ChrX:71476287-71700454 bp, - strand Genetic Position: ChrX, 37.24 cM
• Alliance: Gabra3^tm1Dgen page

Mutation origin

• Mutant Cell Line: 2626
• Germline Transmission: Earliest citation of germline transmission: J:101679
• Parent Cell Line: E14 (ES Cell)
• Strain of Origin: 129P2/OlaHsd
• Project Collection: Deltagen

Mutation description

• Allele Type: Targeted (Null/knockout, Reporter)
• Mutation: Disruption caused by insertion of vector
• Mutation details: A bacterial lacZ gene was inserted into the gene such that the endogenous gene promoter drives expression of beta-galactosidase. RT-PCR analysis detects a high level of gene transcript in the brainstem and olfactory bulb and lower levels in all other tissues analyzed. Beta-galactosidase expression from this allele is detectable in brain, dorsal horns and dorsal root ganglia of the spinal cord and lens of the eye. Expression was also detectable in aorta, a few cells of the heart and kidney, some blood vessels of the lung and liver and tunica albuginea of testis.

Expression

In Mice Carrying this Mutation:

51 assay results

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Gabra3 Mutation: 8 strains or lines available

Notes

See also, data as provided by Deltagen, Inc.

References

• Original: J:101679 Deltagen Inc, NIH initiative supporting placement of Deltagen, Inc. mice into public repositories. MGI Direct Data Submission. 2005
• All: 1 reference(s)