Gabra4^tm1Dgen
Targeted Allele Detail

Summary

• Symbol: Gabra4^tm1Dgen
• Name: gamma-aminobutyric acid type A receptor subunit alpha 4; targeted mutation 1, Deltagen
• MGI ID: MGI:3604588
• Gene: Gabra4 Location: Chr5:71727092-71815651 bp, - strand Genetic Position: Chr5, 38.08 cM
• Alliance: Gabra4^tm1Dgen page

Mutation origin

• Mutant Cell Line: 3066
• Germline Transmission: Earliest citation of germline transmission: J:101679
• Parent Cell Line: E14 (ES Cell)
• Strain of Origin: 129P2/OlaHsd
• Project Collection: Deltagen

Mutation description

• Allele Type: Targeted (Null/knockout, Reporter)
• Mutation: Disruption caused by insertion of vector
• Mutation details: A bacterial lacZ gene was inserted into the gene such that the endogenous gene promoter drives expression of beta-galactosidase. RT-PCR analysis detects a high level of gene transcript in the brain, cortex, subcortical region, cerebellum, olfactory bulb, pancreas and pituitary gland and lower levels in brainstem, spinal cord, eye, Harderian glands, lung, kidney, spleen, lymph nodes, skin, urinary bladder, adrenal gland, salivary gland, tongue, stomach, small intestine, testis, epididymis, seminal vesicle, coagulating gland, prostate gland, ovaries, uterus and white fat. Beta-galactosidase expression from this allele is detectable in brain, spinal cord, pancreas, pituitary gland and salivary glands.

Expression

In Mice Carrying this Mutation:

73 assay results

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Gabra4 Mutation: 43 strains or lines available

Notes

See also, data as provided by Deltagen, Inc.

References

• Original: J:101679 Deltagen Inc, NIH initiative supporting placement of Deltagen, Inc. mice into public repositories. MGI Direct Data Submission. 2005
• All: 1 reference(s)