Ppard^tm1Dgen
Targeted Allele Detail

Summary

• Symbol: Ppard^tm1Dgen
• Name: peroxisome proliferator activator receptor delta; targeted mutation 1, Deltagen
• MGI ID: MGI:3604590
• Gene: Ppard Location: Chr17:28451715-28520446 bp, + strand Genetic Position: Chr17, 14.64 cM
• Alliance: Ppard^tm1Dgen page

Mutation origin

• Mutant Cell Line: 1481
• Germline Transmission: Earliest citation of germline transmission: J:101679
• Parent Cell Line: E14 (ES Cell)
• Strain of Origin: 129P2/OlaHsd
• Project Collection: Deltagen

Mutation description

• Allele Type: Targeted (Null/knockout, Reporter)
• Mutation: Insertion
• Mutation details: A bacterial lacZ gene was inserted into the gene such that the endogenous gene promoter drives expression of beta-galactosidase. RT-PCR analysis detects a gene transcript in all tissues examined; beta-galactosidase expression is detectable in brain, spinal cord, eye, pancreas, kidneys, trachea, larynx, esophagus, pituitary gland, parathyroid gland, tongue, skin, male and female reproductive systems.

Expression

In Mice Carrying this Mutation:

112 assay results

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Ppard Mutation: 68 strains or lines available

Notes

See also, data as provided by Deltagen, Inc.

References

• Original: J:101679 Deltagen Inc, NIH initiative supporting placement of Deltagen, Inc. mice into public repositories. MGI Direct Data Submission. 2005
• All: 1 reference(s)