Grm1^tm1Dgen
Targeted Allele Detail

Summary

• Symbol: Grm1^tm1Dgen
• Name: glutamate receptor, metabotropic 1; targeted mutation 1, Deltagen
• MGI ID: MGI:3604591
• Synonyms: Grm1^tm1deltagen, T801
• Gene: Grm1 Location: Chr10:10561803-10958100 bp, - strand Genetic Position: Chr10, 3.44 cM, cytoband A2
• Alliance: Grm1^tm1Dgen page

Mutation origin

• Mutant Cell Line: 2972
• Germline Transmission: Earliest citation of germline transmission: J:101679
• Parent Cell Line: E14 (ES Cell)
• Strain of Origin: 129P2/OlaHsd
• Project Collection: Deltagen

Mutation description

• Allele Type: Targeted (Null/knockout, Reporter)
• Mutations: Insertion, Intragenic deletion
• Mutation details: A bacterial lacZ gene was inserted into the gene such that the endogenous gene promoter drives expression of beta-galactosidase. RT-PCR analysis detects a gene transcript in the brain spinal cord, eye, heart, skin, tongue and testis; beta-galactosidase expression is detectable in the brain spinal cord, and eye but not in the heart, skin, tongue or testis.

Expression

In Mice Carrying this Mutation:	67 assay results
In Structures Affected by this Mutation:	2 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 3 strains available Cell Lines: 0 lines available
• Carrying any Grm1 Mutation: 81 strains or lines available

Notes

See also, data as provided by Deltagen, Inc.

References

• Original: J:101679 Deltagen Inc, NIH initiative supporting placement of Deltagen, Inc. mice into public repositories. MGI Direct Data Submission. 2005
• All: 7 reference(s)