Pkd2l2^tm1Dgen
Targeted Allele Detail

Summary

• Symbol: Pkd2l2^tm1Dgen
• Name: polycystic kidney disease 2-like 2; targeted mutation 1, Deltagen
• MGI ID: MGI:3604592
• Gene: Pkd2l2 Location: Chr18:34541553-34575842 bp, + strand Genetic Position: Chr18, 18.62 cM, cytoband C
• Alliance: Pkd2l2^tm1Dgen page

Mutation origin

• Mutant Cell Line: 317
• Germline Transmission: Earliest citation of germline transmission: J:101679
• Parent Cell Line: E14 (ES Cell)
• Strain of Origin: 129P2/OlaHsd
• Project Collection: Deltagen

Mutation description

• Allele Type: Targeted (Null/knockout, Reporter)
• Mutation: Disruption caused by insertion of vector
• Mutation details: A bacterial lacZ gene was inserted into the gene such that the endogenous gene promoter drives expression of beta-galactosidase. RT-PCR analysis detects a gene transcript in ubcortical region, cerebellum, heart, pancreas, kidneys, spleen, thymus, lymph nodes, bone marrow and testis; beta-galactosidase expression is detectable in pancreas, testis and ovary.

Expression

In Mice Carrying this Mutation:

50 assay results

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Pkd2l2 Mutation: 46 strains or lines available

Notes

See also, data as provided by Deltagen, Inc.

References

• Original: J:101679 Deltagen Inc, NIH initiative supporting placement of Deltagen, Inc. mice into public repositories. MGI Direct Data Submission. 2005
• All: 2 reference(s)