Kcnq2^tm1Dgen
Targeted Allele Detail

Summary

• Symbol: Kcnq2^tm1Dgen
• Name: potassium voltage-gated channel, subfamily Q, member 2; targeted mutation 1, Deltagen
• MGI ID: MGI:3604594
• Gene: Kcnq2 Location: Chr2:180717372-180777093 bp, - strand Genetic Position: Chr2, 103.57 cM, cytoband H3-4
• Alliance: Kcnq2^tm1Dgen page

Mutation origin

• Mutant Cell Line: 5389
• Germline Transmission: Earliest citation of germline transmission: J:101679
• Parent Cell Line: E14 (ES Cell)
• Strain of Origin: 129P2/OlaHsd
• Project Collection: Deltagen

Mutation description

• Allele Type: Targeted (Null/knockout, Reporter)
• Mutations: Insertion, Intragenic deletion
• Mutation details: A lacZ/IRES/neo cassette replaced sequences corresponding to bases 418 to 535 of the coding region. RT-PCR analysis detects a gene transcript at high levels in brain, spinal cord, pituitary gland and adrenal gland and at lower levels in eye, thymus, lymph nodes, gallbladder, stomach, small intestine, cecum, colon, testis, epididymis, prostate gland, ovary and white fat; beta-galactosidase expression is not detectable in any tissue. (J:142688)

Expression

In Mice Carrying this Mutation:

36 assay results

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Kcnq2 Mutation: 50 strains or lines available

Notes

See also, data as provided by Deltagen, Inc.

References

• Original: J:101679 Deltagen Inc, NIH initiative supporting placement of Deltagen, Inc. mice into public repositories. MGI Direct Data Submission. 2005
• All: 8 reference(s)