Sostdc1^tm1Nit
Targeted Allele Detail

Summary

• Symbol: Sostdc1^tm1Nit
• Name: sclerostin domain containing 1; targeted mutation 1, Nobuyuki Itoh
• MGI ID: MGI:3604658
• Gene: Sostdc1 Location: Chr12:36364168-36368451 bp, + strand Genetic Position: Chr12, 16.82 cM, cytoband B2
• Alliance: Sostdc1^tm1Nit page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:101382
• Parent Cell Line: CJ7 (ES Cell)
• Strain of Origin: 129S1/Sv-Oca2⁺ Tyr⁺ Kitl⁺

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• The first two exons were replaced with an IRES-LacZ-polyA/PGK-neo cassette. (J:101382)

Expression

In Mice Carrying this Mutation:	17 assay results
In Structures Affected by this Mutation:	2 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Sostdc1 Mutation: 28 strains or lines available

References

• Original: J:101382 Kassai Y, et al., Regulation of mammalian tooth cusp patterning by ectodin. Science. 2005 Sep 23;309(5743):2067-70
• All: 6 reference(s)