Ugcg^tm1.1Hjg
Targeted Allele Detail

Summary

• Symbol: Ugcg^tm1.1Hjg
• Name: UDP-glucose ceramide glucosyltransferase; targeted mutation 1.1, Hermann-Josef Grone
• MGI ID: MGI:3604764
• Gene: Ugcg Location: Chr4:59189452-59222833 bp, + strand Genetic Position: Chr4, 32.44 cM, cytoband B3
• Alliance: Ugcg^tm1.1Hjg page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:101155
• Parent Cell Line: E14 (ES Cell)
• Strain of Origin: 129P2/OlaHsd

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutation: Intragenic deletion
• Cre mediated recombination of Ugcg^tm1Hjg removed the sequence between introns 5 and 8. (J:101155)

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Ugcg Mutation: 87 strains or lines available

References

• Original: J:101155 Jennemann R, et al., Cell-specific deletion of glucosylceramide synthase in brain leads to severe neural defects after birth. Proc Natl Acad Sci U S A. 2005 Aug 30;102(35):12459-64
• All: 2 reference(s)