Taf10^tm1.1Lzt
Targeted Allele Detail

Summary

• Symbol: Taf10^tm1.1Lzt
• Name: TATA-box binding protein associated factor 10; targeted mutation 1.1, Laszlo Tora
• MGI ID: MGI:3605460
• Synonyms: TAF10^-
• Gene: Taf10 Location: Chr7:105392101-105393550 bp, - strand Genetic Position: Chr7, 55.97 cM, cytoband F1
• Alliance: Taf10^tm1.1Lzt page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:101819
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: 129

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutation: Intragenic deletion
• Mutation details: Cre mediated recombination by mating to Tg(CMV-cre)1Ipc mice was used to remove exon 2. Deletion of exon 2 introduces a frame shift followed by a premature termination codon, thus producing a null allele. (J:101819)

Expression

In Mice Carrying this Mutation:	1 RNA-Seq or microarray experiment(s)
In Structures Affected by this Mutation:	2 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Taf10 Mutation: 13 strains or lines available

References

• Original: J:101819 Mohan WS Jr, et al., TAF10 (TAF(II)30) is necessary for TFIID stability and early embryogenesis in mice. Mol Cell Biol. 2003 Jun;23(12):4307-18
• All: 2 reference(s)