Prdm1^tm2Rob
Targeted Allele Detail

Summary

• Symbol: Prdm1^tm2Rob
• Name: PR domain containing 1, with ZNF domain; targeted mutation 2, Elizabeth J Robertson
• MGI ID: MGI:3605483
• Synonyms: prdm1^BEH
• Gene: Prdm1 Location: Chr10:44313173-44404497 bp, - strand Genetic Position: Chr10, 23.24 cM
• Alliance: Prdm1^tm2Rob page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:101718
• Parent Cell Line: CCE/EK.CCE (ES Cell)
• Strain of Origin: 129S/SvEv-Gpi1^c

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: The insertion of a loxP flanked pgk-hygro cassette resulted in a deletion beginning upstream of the ATG in exon 1 and including exon 3. (J:101718)

Expression

In Mice Carrying this Mutation:	34 assay results 3 RNA-Seq or microarray experiment(s)
In Structures Affected by this Mutation:	8 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Prdm1 Mutation: 66 strains or lines available

References

• Original: J:101718 Vincent SD, et al., The zinc finger transcriptional repressor Blimp1/Prdm1 is dispensable for early axis formation but is required for specification of primordial germ cells in the mouse. Development. 2005 Mar;132(6):1315-25
• All: 9 reference(s)