Fgfr1^tm1Swnr
Targeted Allele Detail

Summary

• Symbol: Fgfr1^tm1Swnr
• Name: fibroblast growth factor receptor 1; targeted mutation 1, Sabine Werner
• MGI ID: MGI:3606056
• Synonyms: FGFR1-IIIb^-
• Gene: Fgfr1 Location: Chr8:26008808-26067819 bp, + strand Genetic Position: Chr8, 14.12 cM
• Alliance: Fgfr1^tm1Swnr page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:101854
• Parent Cell Line: AB2.2 (ES Cell)
• Strain of Origin: 129S7/SvEvBrd-Hprt1^b-m2

Mutation description

• Allele Type: Targeted (Modified isoform(s), Null/knockout)
• Mutation: Intragenic deletion
• Mutation details: Exon 6, the exon specific to the IIIb variant, was excised by cre-mediated recombination. Transcript was not detected in mutant animals. (J:101854)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Fgfr1 Mutation: 223 strains or lines available

References

• Original: J:101854 Zhang H, et al., Fibroblast growth factor receptor 1-IIIb is dispensable for skin morphogenesis and wound healing. Eur J Cell Biol. 2004 Feb;83(1):3-11
• All: 3 reference(s)