Rb1^tm3.1Tyj
Targeted Allele Detail

Summary

• Symbol: Rb1^tm3.1Tyj
• Name: RB transcriptional corepressor 1; targeted mutation 3.1, Tyler Jacks
• MGI ID: MGI:3606968
• Gene: Rb1 Location: Chr14:73430298-73563446 bp, - strand Genetic Position: Chr14, 38.73 cM, cytoband D3
• Alliance: Rb1^tm3.1Tyj page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:81643
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutation: Intragenic deletion
• Exon 3 was removed by Cre-mediated recombination of Rb1^tm3Tyj. (J:81643)

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Rb1 Mutation: 111 strains or lines available

References

• Original: J:81643 MacPherson D, et al., Conditional mutation of Rb causes cell cycle defects without apoptosis in the central nervous system. Mol Cell Biol. 2003 Feb;23(3):1044-53
• All: 1 reference(s)