Uts2r^tm1Djbe
Targeted Allele Detail

Summary

• Symbol: Uts2r^tm1Djbe
• Name: urotensin 2 receptor; targeted mutation 1, David J Behm
• MGI ID: MGI:3608769
• Synonyms: UT-
• Gene: Uts2r Location: Chr11:121051097-121052799 bp, + strand Genetic Position: Chr11, 85.02 cM
• Alliance: Uts2r^tm1Djbe page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:103118
• Parent Cell Line: E14.1 (ES Cell)
• Strain of Origin: 129P2/OlaHsd

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• The single coding exon was replaced with a neo cassette via homologous recombination. (J:103118)

Expression

In Structures Affected by this Mutation:

2 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Uts2r Mutation: 26 strains or lines available

References

• Original: J:103118 Behm DJ, et al., Deletion of the UT receptor gene results in the selective loss of urotensin-II contractile activity in aortae isolated from UT receptor knockout mice. Br J Pharmacol. 2003 May;139(2):464-72
• All: 2 reference(s)