Gjc1^tm2.1Kni
Targeted Allele Detail

Summary

• Symbol: Gjc1^tm2.1Kni
• Name: gap junction protein, gamma 1; targeted mutation 2.1, Kiyomasa Nishii
• MGI ID: MGI:3608792
• Gene: Gjc1 Location: Chr11:102690405-102710526 bp, - strand Genetic Position: Chr11, 66.48 cM
• Alliance: Gjc1^tm2.1Kni page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:103078
• Parent Cell Line: CCE/EK.CCE (ES Cell)
• Strain of Origin: 129S/SvEv-Gpi1^c

Mutation description

• Allele Type: Targeted (Null/knockout, Reporter)
• Mutations: Insertion, Intragenic deletion
• Mutation details: Cre-mediated recombination removed the single coding exon leaving behind an nls-LacZ reporter construct. (J:103078, J:231835)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Gjc1 Mutation: 33 strains or lines available

References

• Original: J:103078 Nishii K, et al., Mice lacking connexin45 conditionally in cardiac myocytes display embryonic lethality similar to that of germline knockout mice without endocardial cushion defect. Cell Commun Adhes. 2003 Jul-Dec;10(4-6):365-9
• All: 2 reference(s)